Low Dose Naltrexone (LDN) is a modified, low-dose version of the FDA-approved drug naltrexone, which is traditionally used to treat alcohol and opioid dependence.
In small doses (typically 0.5 mg to 8 mg), LDN is prescribed off-label to help with appetite regulation, inflammation control, autoimmune support, and hormonal rebalancing—making it a powerful addition to medically supervised weight loss programs.
LDN works by modulating the immune system, reducing inflammation, and temporarily blocking opioid receptors, which leads to a rebound increase in endorphin and dopamine production—improving mood, motivation, and metabolism.
*Final price to patient will depend on medication dosage and membership plan purchase.
✅ Adults with a BMI ≥30, or ≥27 with conditions like PCOS, insulin resistance, or prediabetes
✅ Those who don’t qualify for—or can’t afford—brand-name GLP-1s
✅ Patients seeking medically managed weight loss with ongoing support
✅ Anyone committed to sustainable, health-focused fat loss
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Your provider evaluates your goals, history & labs
If appropriate, you’ll receive a Low Dose Naltrexone prescription
All medications come with full instructions
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Customer was compensated for their opinion. Results have not been independently verified. Individual results will vary.
When taken consistently, and as part of a personalized treatment plan, LDN may help:
💊 Naltrexone
Starting at $59/month — includes prescription, shipping, and refill coordination.
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No. LDN is not FDA-approved for any specific condition. It is prescribed off-label based on emerging evidence that shows it may help with autoimmune disease, weight control, and inflammation when used at low doses.
LDN temporarily blocks opioid receptors, triggering a rebound in natural endorphins and dopamine. This leads to better mood, fewer cravings, improved control over emotional eating, and reduced inflammation—especially in metabolically resistant patients.
Regular naltrexone is prescribed at 50–100 mg/day to treat addiction. LDN uses a much lower dose—typically 0.5–4.5 mg/day—to influence immune and metabolic pathways without blocking all opioid activity.
LDN is especially helpful for patients with:
Yes. LDN is often combined with metformin, bupropion, GLP-1 medications (semaglutide/tirzepatide), or thyroid medications as part of a personalized protocol.
LDN is generally well tolerated. Some patients report vivid dreams, temporary sleep changes, or mild GI discomfort at first. These effects are usually mild and resolve with dose adjustment.
LDN is taken orally, once daily, often at night. Dosing starts low (e.g. 0.5–1 mg) and is slowly increased over several weeks to reach the ideal level for each patient.
Low Dose Naltrexone (LDN) is a compounded, off-label version of the FDA-approved medication naltrexone. It is not FDA-approved for any specific medical condition and has not been evaluated by the FDA for safety, efficacy, or manufacturing standards in compounded form.
LDN is compounded in doses far lower than the standard 50–100 mg used in addiction treatment. It is prepared by licensed 503A compounding pharmacies and prescribed by healthcare providers when clinically appropriate based on individual goals.
LDN is generally well tolerated but should not be used by individuals taking opioid pain medications, as it may interfere with pain relief or trigger withdrawal symptoms. Patients must disclose all current medications to their provider before starting LDN.
While side effects are uncommon, they may include:
LDN is not a stimulant, is not habit-forming, and does not suppress appetite in the traditional sense—it works indirectly through mood, craving, and inflammation pathways.
Always follow your provider’s guidance. Do not adjust your dose or combine medications without medical supervision.
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